AFIX Capsule

Therapeutic Class



Upper respiratory tract infections: Otitis media and other URTI where the causative organism is known or suspected to be resistant to other commonly used antibiotics. Lower respiratory tract infection: Bronchitis. Urinary tract infections: Cystitis, cystourethritis, pyelonephritis, gonococcal urethritis. Gonorrhoea (Uncomplicated). Typhoid fever.

Chemical Composition

Cefixime BP 200 mg


1 x 10's/ Box

Dosage & Administration

The usual course of treatment is 7 days. This may be continued for up to 14 days if required. Afix® Tablet & Capsule: Adult & Child over 10 years: 200-400 mg daily 1-2 divided doses. Gonorrhoea: 400 mg as a single dose.


Cefixime is contraindicated in patients with known hypersensitivity to the cephalosporin antibiotics.

Side Effects

Afix® is generally well tolerated. The majority of adverse reactions observed in clinical trials were mild and self-limiting in nature. Gastro-intestinal disturbances: Diarrhoea (if severe diarrhoea occurs, Afix® should be discontinued), changes in the color of stool, nausea, abdominal pain, dyspepsia, vomiting, flatulence have been reported. Central nervous system disturbances: Headache, dizziness etc. Others: Hypersensitivity reactions which usually subsided upon discontinuation of therapy; infrequent and reversible haematological changes; elevation of serum amylase etc.

Drug Interaction

Carbamazepine: Elevated carbamazepine levels have been reported. Warfarin and Anticoagulants: Increased prothrombin time with or without clinical bleeding has been reported when cefixime is administered concomitantly.