AFRIN Nasal drop

Therapeutic Class

Nasal Decongestants & Other Nasal Preparations


Nasal congestion associated with Fs ® Allergic & Infectious Rhinitis ® Sinusitis ® Common cold

Chemical Composition

Afrin Nasal Drops: Each ml nasal drop contains Oxymetazoline HCI USP 0.5 mg.
Afrin Paediatric Nasal Drops: Each ml nasal drop contains Oxymetazoline HCI USP 0.25 mg.
Preservative: Benzalkonium Chloride Solution BP 0.02%.


10 ml / Bot

Dosage & Administration

2 to 3 drops should be instilled into each nostril twice daily. The drops should be instilled into the nose, one nostril at a time, in the head-low position to reduce the risk of the patient swallowing any of the solution.Treatment course should not normally exceed 3 to 5 days and on no account should it be continued for longer than 2 weeks.


MAO inhibitor, tricyclic antidepressant.

Side Effects

Stinging, discomfort or a dryness locally in the nose are encountered infrequently. Headache has also been reported. Prolonged use may lead to rebound vasodilatation (drug-induced rhinitis). Overuse may result in sedation in children. Oxymetazoline may also result in short-lived rise “in pressure, followed by prolonged hypotension and sedation.

Drug Interaction

Oxymetazoline causes hypertensive crisis if used simultaneously with MAO inhibitor or tricyclic antidepressant.