HEPAXIMIN 550 Tablet

Therapeutic Class

Other Antibiotics

Indications

Acute infectious diarrhoea including travelers diarrhoea, Diarrhoea predominant Irritable Bowel Syndrome (IBS-D), Hepatic Encephalopathy (H.E.)

Chemical Composition

Each film-coated tablet contains Rifaximin BP 550 mg.

Packaging

Each box contains 10's tablets in alu-alu blister pack.

Dosage & Administration

Acute Infectious Diarrhoea including Travelers Diarrhoea: 200 mg three times daily for 3 days. Diarrhoea predominant Irritable Bowel Syndrome (IBS-D: 550 mg three times daily for 14 days. Hepatic Encephalopathy (H.E.): 550 mg twice daily

Contraindications

Hepaximin is contraindicated in patients with a hypersensitivity to Rifaximin, or any of the Rifamycin antimicrobial agents, or any of the components of this preparation

Side Effects

Common side effects are nausea, vomiting, abdominal pain, flatulence, headache and dizziness

Drug Interaction

Although In vitro studies demonstrated the potential of Rifaximin to interact with cytochrome P450 (CYP3A4), a clinical drug-drug interaction study demonstrated that Rifaximin did not significantly affect the pharmacokinetics of midazolam. An additional clinical drug-drug interaction study showed no effect of Rifaximin on the presystemic metabolism of an oral contraceptive containing ethinyl estradiol and norgestimate. Therefore, clinical interactions with drugs metabolized by human cytochrome P450 isozymes are not expected.