LODIPIN – 5 Tablet
Therapeutic Class
Calcium Antagonists
Indications
1. Hypertension: Lodipin is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents. 2. Stable angina: Lodipin is indicated for the treatment of stable angina. It may be used alone or in combination with other antianginal agents. 3. Vasospastic angina: Lodipin is indicated for the treatment of confirmed or suspected vasospastic angina. It may be used as monotherapy or in combination with other antianginal agents.
Chemical Composition
Lodipin 5 Tablet: Each tablet contains Amlodipine besylate BP equivalent to Amlodipine 5 mg.
Packaging
Lodipin 5 Tablet: Each box contains 60's tablets in blister pack.
Dosage & Administration
Hypertension or angina: Initially 5 mg once daily; max 10 mg once daily.
Contraindications
Amlodipine is contraindicated in patients with known hypersensitivity to Amlodipine.
Side Effects
Peripheral edema may occasionally be severe but is fully reversible. And as with other calcium antagonist drugs, peripheral edema and skin erythema occur in a proportion of patients (5-10%) and facial flushing in 2.5% of patients. Complaints of fatigue was also reported more frequently than in placebo-treated patients. There is evidence that these effects are more common in patients treated with doses greater that 10 mg daily. Clinical experience with Amlodipine is still relatively limited and as this increases, a more reliable assessment of toxicity and side effects can be provided.
Drug Interaction
Digoxin: Absence of any interaction between Amlodipine and Digoxin in healthy volunteers has been documented in controlled clinical study. Cimetidine: An unpublished clinical study indicated no interaction between Amlodipine and Cimetidine in healthy volunteers. Warfarin: An unpublished study in healthy volunteers indicates that Amlodipine did not significantly alter the effect of Warfarin on prothrombin time. We all love high-end patek philippe replica watches which are really rare. Food: Food does not alter the rate or extent of absorption of Amlodipine.