NEUROPANE 100 Capsule

Therapeutic Class



NEUROPANE 100 is indicated: As an adjunct to other standard anticonvulsant medications in patients who have not achieved adequate seizure control with these agents used alone or in combination. In controlling both simple and complex partial seizures with or without secondarily generalized tonic clonic seizures.

Chemical Composition

Gabapentin BP : 100mg
Excipients : Q.S.
Approved colors used in empty capsule shells.


3 x 10's/ Box

Dosage & Administration

Adults and children over 12 years; Initially 300 mg three times a day. The dosage may be gradually increased based on the clinical response. Dosages of 900 to 1800 mg per day taken in three divided doses with not more than 12 hours between doses are effective for most patients. Dosages of up to 3600 mg in divided doses three times a day for short periods have been well tolerated.


Hypersensitivity to gabapentin or the product's excipients. Safety and efficacy in children under 12 years has not been established. Safety and efficacy in pregnancy and lactation has not been established.

Warning & Precautions

Patients should be warned that NEUROPANE 100 may affect their alertness and that caution should be exercised when driving a vehicle, operating machinery or performing hazardous tasks. The concomitant use of alcohol will intensity these effects. NEUROPANE 100 should be used with caution in patients with a history of psychotic illness. It should also be used with caution in renal impairment. Abrupt withdrawal of NEUROPANE 100 in epileptic patients may precipitate status epilepticus. Should it be required to reduce the dosage, discontinue the treatment or substitute with another anticonvulsant medicine, it should be done gradually over a minimum of one week.

Side Effects

Nervous system disorders Frequent: Fatigue, somnolence, dizziness, ataxia, tremor, vertigo. Less frequent: Headache, dysarthria, amnesia, confusion, insomnia, twitching, abnormal co-ordination, paraesthesia, nervousness.

Drug Interaction

There is no interaction between NEUROPANE 100, phenobarbitone, phenytoin, valproic acid, carbamazepine or carbamazepine-10,11- epoxide. Co-administration of NEUROPANE 100 with oral contraceptives, containing norethindrone and/or ethinyl estradiol, does not influence the steady-state plasma concentrations of either component. Concomitant use of NEUROPANE 100 with a magnesium- and aluminium-containing antacid reduces gabapentin bioavailability by approximately 20%. It is recommended that gabapentin be taken about two hours following antacid administration. Concurrent use of NEUROPANE 100 with alcohol and other CNS depressants may increase the CNS depressant effects. False positive tests for proteinuria may occur with Ames Multistix-SG.

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