Therapeutic Class

Antifungal with Corticosterioids


Uniflex-N Cream is indicated for the relief of corticosteroid-responsive inflammatory dermatoses, especially when secondary bacterial infection is present or likely to be present. It is indicated for the treatment of eczema, psoriasis, lichen planus, seborrhoeic dermatitis, intertrigo, contact sensitivity reactions, discoid lupus erythematosus, generalised erythroderma. Uniflex-N can be used for the relief of insect bites and stings.

Chemical Composition

Contains Miconazole Nitrate 2% w/w and Hydrocortisone 1% w/w in a non greasy, non-staining cream basis. Benzoic Acid 0.15% w/w as preservative.


15 g / Tube

Dosage & Administration

For external use only. Clean the skin before applying this medicine. Apply a thin layer to completely cover the affected areas once or twice daily and rub well to ensure good absorption. Continue to use this medicine for at least one week after disappearance of symptoms to completely destroy the fungus which may still be present. For nail infections, apply daily and cover with bandage.


Do not use for other skin problems without first checking with your doctor. Topical hydrocortisone should not be used in patients with tuberculosis and herpes simplex infections and also in patients vaccinated with live vaccine.

Warning & Precautions

Before using this medicine, check with your doctor if you are pregnant or intending to conceive or are breast feeding. Inform your doctor if you have any previous unusual or allergic reactions to any topical preparation. Use with care on children especially when applied to large areas or with occlusive dressing. Do not bandage or otherwise cover the area of skin being treated unless directed by the doctor. Such an occlusive dressing (airtight covering) may increase both the amount of steroid absorbed through the skin as well as increase the risk of side effect. Avoid contact with your eyes. It is advisable to consult a doctor if no improvement is observed in 4 weeks in the case of 'athlete's foot' or 2 weeks in 'jock itch. In patients on warfarin, caution should be exercised and the anticoagulant effect should be monitored (see Interactions). Visual disturbance may be reported with systemic and topical corticosteroid use. If a patient presents with symptoms such as blurred vision or other visual disturbances, the patient should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma or rare diseases such as central serous chorioretinopathy (CSCR) which have been reported after use of systemic and topical corticosteroids.

Side Effects

Check with your doctor if your skin problems become worse or if there is redness, swelling, pain, itch, stinging or irritation at the site of application. The following side effects may occur if you use this medicine for a long time: acne or oily skin; filling or rounding out of the face; reddish stretch marks; thinning of skin with easy bruising; unusual weakness; swelling of the feet or legs; wounds that will not heal; persistent sore throat

Drug Interaction

Miconazole administered systemically is known to inhibit CYP2C9 enzyme system. Due to the limited systemic availability after topical application, clinically relevant interactions occur very rarely. In patients on warfarin which is subjected to metabolism by CYP2C9, caution should be exercised and the anticoagulant effect should be monitored. (See Warnings and Precautions).